Kids* deserve protection from infection too.

*Two years of age and older.

You’re in the right place to learn about HyQvia® [Immune Globulin Infusion 10% (Human) with Recombinant Human Hyaluronidase] for kids and teens.

If you’re here, you’re likely a parent, caregiver, or pretty smart kid or teen seeking more information about PI and HyQvia. Maybe a doctor has mentioned the possibility of PI, there’s been a diagnosis, or you are new to HyQvia. However you found us, we’re so glad you’re here. You’ll find all kinds of info about PI, HyQvia, and what can be done to make your kiddo or teen feel more comfortable with infusions.

One of the main reasons parents come here is because of how infrequently their child may be able to infuse—up to every 28 days. That’s monthly infusions (every 3 or 4 weeks). Plus, infusing at home is a possibility too, with the protection from infection your child needs. Your child’s doctor will help you decide what’s best, but the possibility is there. Which is great because life is busy, and so are kids!

With HyQvia, your child may be able to infuse monthly
(every 3 or 4 weeks).

That’s once a month, as opposed to more frequent infusions. HyQvia is the only monthly subQ IG treatment. This flexible dosing schedule, prescribed by your child's doctor, allows your child to minimize the impact infusing can have on their daily routine. So, whether they just love to play, read, or they have a busy schedule, they may be able to do more of it because of fewer infusions per month.

Stopwatch icon.

How long is an average infusion?

HyQvia infusions were approximately an hour and a half in a study of 44 pediatric patients. (Coincidentally, the same amount of time as a movie.)

Hy and Ig letters inside of two circles depicting how HyQvia works.

So how is this possible?

Hyaluronidase, or hy. Hy allows the body to absorb more IG, the medicine your child needs to help fight infections. Hy is infused first, followed by the IG.

Home and hospital icon.

With HyQvia, there are infusion options to fit every comfort level.

Your child has the option to infuse at home or in a center, and self-infusion (after appropriate training) or infusion with nurse assistance. You, your child, and the doctor can decide what’s right. It really depends on you and your child’s comfort level.


How effective is HyQvia for children?

Let’s start with the study.

In pediatric patients, the study showed us there were:

•  0.04 acute serious bacterial infections (ASBIs) per patient-year      

— One subject experienced two ASBIs of bacterial pneumonia

— This is equivalent to 40 ASBIs out of 1,000 patients over the course of the 12-month study period

— This is significantly less than the FDA standard for an IG medicine to be effective!

•  3.20 infections of any kind per patient-year, which is consistent with results in the adult clinical trial

Yellow and purple infection icon.

0.04 ASBIs
per patient-year with HyQvia

Yellow calendar icon with 3 purple squares.

~3 infections
per patient-year

Let’s back up for a sec in case you’re wondering what ASBIs are.

ASBIs are short-term but serious infections caused by bacteria that require immediate medical care. The FDA standard for efficacy—that is, if an immunoglobulin works—is less than 1 ASBI per year. In the clinical trial, people taking HyQvia experienced significantly less than that.

About the study

HyQvia was studied in a clinical trial of 44 pediatric patients with PI. The main goal of the study was to measure how many acute serious bacterial infections (ASBIs) they experienced over the course of 1 year.

Most children completed their infusions without interruption.

In a 12-month study of 2- to 16-year-olds:

•    99.8% of infusions were completed
•    94.1% were completed without interruption
•    The safety results for pediatrics were similar
     to those of adults

99.8% pie graph.

of infusions were completed

The most common adverse reactions observed in >5% of patients in the clinical trials were: local adverse reactions including pain, erythema, edema, and pruritus, and systemic adverse reactions including headache, antibody formation against Recombinant Human Hyaluronidase (rHuPH20), fatigue, nausea, pyrexia, and vomiting.


What can your child do during the infusion?

Great question. We know that it’s hard for kids to sit still. Period. No matter the age. The key to helping them through their infusion is to tap into their interests. Does your child love to craft? Stock up on crafting supplies and bust ’em out for their infusion. Does your child love to play video games? Let ’em play a little longer. Here are a few other ideas:

Video call icon.

Video call with grandma,
grandpa, aunts, uncles,
cousins, friends

Reading book icon.

Read a book
or magazines

Two dice icon.

Play board

Pen holder icon.

Color, draw,

Journal and pen icon.

(if they’re older)

Building block icon.

Create something with
building bricks

Living room icon.

What else helps?

Make a designated space for infusions that’s all theirs. It could have their favorite toys or stuffies, blankets, a pillow, pictures they love, etc. What we’re going for here is anything that will make them feel more comfortable. And it’s nice to have that to look forward to and help make the infusion experience more positive.

Fort icon.

Build a fort!

If they’re still into imaginary playlands, make a special fort they can sit in during their infusion. (Safely, holding still of course.) They can pretend they’re on a pirate ship or in an igloo—their imagination is the limit.

Want to know what it’s like to infuse?

Learn the different ways to infuse from start to finish.

Cellphone and syringe icon.
Cellphone and syringe icon.
"hy, summer camp" quote.

*Between infusions, based on administration every 3 or 4 weeks.

This guide can help you
talk with your doctor.

Our Doctor Discussion Guide can help you get your thoughts together, craft responses, and help you think of other questions you may have.

Want to learn more about paying for HyQvia?

Understandable. Here’s a link
to helpful co-pay info.

Ask your doctor about
a free trial program.

HelloHYQVIA is a free trial program your child can be enrolled in (if eligible) that covers the entire cost of their first three infusions and supplies.