HYQVIA is a liquid medicine that is given under the skin (subcutaneously) to treat primary immunodeficiency (PI) in adults.

How HyQvia works

Unique treatment component.
Once-a-month* infusions.

HYQVIA works by offering a unique treatment component.

*Every 3 or 4 weeks.

What makes HyQvia different? Recombinant Human Hyaluronidase.

HyQvia [Immune Globulin Infusion 10% (Human) with Recombinant Human Hyaluronidase] is the only once-a-month* Ig with Recombinant Human Hyaluronidase. It’s the reason you can infuse HyQvia once a month.*

Recombinant Human Hyaluronidase is also known as Hy. As the first of two parts of your HyQvia infusion, the Hy temporarily opens the space under your skin (subQ space), allowing for a larger amount of Ig to reach your subQ tissue and be absorbed into your bloodstream to help your body fight infections—so you don’t have to infuse as many times per month.

In the clinical trials, there were no observable changes in the skin or subQ tissue in almost 3000 infusions and maximum exposure of over 3 years. After HYQVIA infusion, a temporary, soft swelling may occur around the infusion site, which may last 1 to 3 days due to the volume of fluid infused. The effect of Hy is reversible and your skin's permeability will be restored within 24 to 48 hours following your infusion.

*Every 3 or 4 weeks.
2959 infusions and ~3.5 subject-years.

HyQvia vial


Hyaluronidase (Hy)

Infused first, Hy opens the subQ space to allow for a larger amount of Ig.


Immune globulin (Ig)

Infused second, Ig includes the antibodies that help your body fight infections.

HYQVIA [Immune Globulin Infusion 10% (Human) with Recombinant Human Hyaluronidase] uses Ig antibodies and Recombinant Human Hyaluronidase

Dual-vial unit.
One infusion.

HyQvia is supplied as a dual-vial unit that allows you to infuse Hy, then Ig, at the same site. You can work with your doctor to use one or two infusion sites, depending on what’s right for you. Ready to learn more about infusing HyQvia?

How to take HyQvia

More days between infusions.
Less time thinking about her treatment schedule.

Meet Angela.

Avid runner. Mother of 3. Angela sets her own pace in life, not her PI. She chooses HyQvia so she can maximize her time inbetween infusions.